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Stanford vs. USC odds, line: 2021 college football picks, Week 2 predictions from proven computer model

Stanford vs. USC odds, line: 2021 college football picks, Week 2 predictions from proven computer model

The Stanford Cardinal and the USC Trojans are set to square off in a Pac-12 matchup at 10:30 p.m. ET on Saturday, September 11 at United Airlines Field at the Los Angeles Memorial Coliseum. USC (1-0) won their season opener against San Jose State in impressive fashion, while Stanford (0-1) lost to Kansas State 24-7 in their first game of the 2021 college football season.

The Trojans (1-0) are 17-point favorites over Stanford (0-1) in the latest USC vs. Stanford odds from Caesars Sportsbook, and the over-under for total points scored is set at 52.5. Before locking in any Stanford vs. USC picks, you’ll want to see the college football picks and predictions from the proven computer model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of over $3,500 for $100 players on its top-rated college football picks against the spread. It also enters Week 2 of the 2021 season on a 63-45 run on all top-rated college football picks. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on USC vs. Stanford and just revealed its picks and predictions. You can head to SportsLine now to see its picks. Here are several college football odds and betting trends for USC vs. Stanford:

  • USC vs. Stanford spread: USC -17
  • USC vs. Stanford over-under: 52 points
  • USC vs. Stanford moneyline: USC -900, Stanford +600

Featured Game | USC Trojans vs. Stanford Cardinal

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What you need to know about USC

USC was impressive on both sides of the ball in their decisive win over the San Jose State last week. Quarterback Kedon Slovis was sharp, completing 24-of-36 passed for 258 yards and two touchdowns. Junior wide receiver Drake London caught 12 passes for 137 yards against the Spartans.

Defensively, the Trojans were dominant in their season opener, forcing two turnovers and allowing 376 total yards, with only 68 of those yards coming on the ground. Given Stanford’s run-heavy offense, USC formidable rush defense could give them a major advantage.

What you need to know about Stanford

Meanwhile, the contest between Stanford and the Kansas State Wildcats last week was not a total blowout, but with Stanford falling 24-7, it was dangerously close to turning into one. One thing working slightly against Stanford was the very average performance of their most targeted running back, Austin Jones, who rushed for 25 yards on nine carries.

Stanford will have to execute much better on both sides of the ball than they did against Kansas State to avoid being blown out by the Trojans on Saturday night.

How to make USC vs. Stanford picks

The model has simulated USC vs. Stanford 10,000 times and the results are in. We can tell you that the model is leaning over on the point total, and it’s also generated a point-spread pick that is hitting in 60 percent of simulations. You can only see the model’s Stanford vs. USC pick at SportsLine.

So who wins USC vs. Stanford? And which side of the spread hits 60 percent of the time? Visit SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks, and find out.

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