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Louisville vs. DePaul odds, line: 2021 college basketball picks, Dec. 10 predictions from proven model

Louisville vs. DePaul odds, line: 2021 college basketball picks, Dec. 10 predictions from proven model

The DePaul Blue Demons will take on the Louisville Cardinals at 8 p.m. ET on Friday at the KFC Yum! Center. Louisville is 6-2 overall and 3-1 at home, while the Blue Demons are 7-1 overall and 0-0 on the road. The programs were conference foes in the old Big East and in Conference USAm but this will be the first time that the two schools have met since 2013.

DePaul is an excellent 7-1 against the spread in 2021-22, while Louisville has been a more modest 4-4 against the number. The Cardinals are favored by 7.5 points in the latest Louisville vs. DePaul odds from Caesars Sportsbook and the over-under is set at 146. Before entering any DePaul vs. Louisville picks, you’ll want to see the college basketball predictions from the model at SportsLine.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of over $2,200 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Louisville vs. DePaul. You can head to SportsLine to see its picks. Here are several college basketball odds for DePaul vs. Louisville:

  • Louisville vs. DePaul spread: Louisville -7.5
  • Louisville vs. DePaul over-under: 146 points

Featured Game | Louisville Cardinals vs. DePaul Blue Demons

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What you need to know about Louisville

Even if it wasn’t a dominant performance, U of L beat the NC State Wolfpack 73-68 on Saturday. The Cardinals got double-digit scores from five players: forward Malik Williams (14), forward Matt Cross (13), guard Noah Locke (12), guard Dre Davis (11) and guard El Ellis (11).

After failing to make the NCAA Tournament last season, Chris Mack worked the transfer market to bring Locke in from Florida and Cross in from Miami (Fla.). He also brought in former Marshall point guard Jarrod West to add backcourt depth. Unfortunately, shooting has been an issue for the Cardinals, as they make just 30.6 percent of their 3-point attempts and rank 287th nationally in that category.

What you need to know about DePaul

Meanwhile, the Blue Demons took their game against the Duquesne Dukes on Tuesday by a conclusive 87-67 score. Among those leading the charge for DePaul was guard Javon Freeman-Liberty, who had 26 points and five assists along with nine rebounds.

The product of Chicago’s Whitney Young HS transferred from Valparaiso after his sophomore season and averaged 14.4 points per game in 14 contests last season. But he’s elevated his game in 2021-22, averaging 21.8 points, 8.8 rebounds, 4.3 assists and 1.9 steals per game. He’s the heart and soul of a rejuvenated Blue Demons squad that is off to a great start in in long-time Oregon assistant Tony Stubblefield’s first season at the helm of the program.

How to make DePaul vs. Louisville picks

The model is leaning under on the total and it’s also generated a point-spread pick that is hitting in over 50 percent of simulations. You can only see the pick at SportsLine.

So who wins Louisville vs. DePaul? And which side of the spread hits over 50 percent of the time? Visit SportsLine now to find out, all from the red-hot model that has crushed its college basketball picks.

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