Two-way star Shohei Ohtani will look to stay hot when he takes the mound for the Los Angeles Angels on Wednesday against the Chicago White Sox in Anaheim, Calif. Ohtani (6-4, 2.90 ERA) has won three straight starts and has given up only one run in 20 innings. He will face Chicago’s Michael Kopech (2-4, 2.59) who has a 5.23 ERA across five June starts. Los Angeles is a -190 favorite in the latest Angels vs. White Sox odds from Caesars Sportsbook while Chicago is a +170 underdog.
First pitch is set for 9:38 p.m. ET at Angel Stadium. The game is one of 15 on the MLB schedule for Wednesday. Elsewhere in the majors, Justin Verlander and the Astros look to finish a two-game sweep of the Mets, and the Blue Jays go for a three-game sweep of the Red Sox. Before making any MLB picks or parlays, be sure to check out the MLB predictions and betting advice from SportsLine’s proven computer model.
The SportsLine Projection Model simulates every MLB game 10,000 times and it is off to a strong start to the 2022 season. It’s on a 59-51 run on top-rated MLB money-line picks through 12 weeks. This is the same model that pegged the 2021 Atlanta Braves at 10-1 as one of three best bets to win it all last season. Anybody who has followed it has seen profitable returns.
Now, the model has locked in three confident MLB best bets for Wednesday. They all involve games at 8:05 p.m. ET or later, so there’s still time to get these MLB picks in. If you successfully parlay the picks, you’d be looking at a payout of 10-1. You can see the model’s MLB picks for Wednesday only at SportsLine.
Top MLB picks today
After simulating every game on Wednesday 10,000 times, the model is high on the Reds (+115) to beat the Cubs at 8:05 p.m. ET (see tickets at StubHub). Cincinnati (26-47) has won three of its last four and sits in fifth in the NL Central. Chicago (28-46) has lost two of its last three and is just 1.5 games ahead of the Reds in the division.
The Cubs pitching has struggled mightily this month as in June, Chicago has an ERA of 6.04. That’s the worst in the majors over that time and almost one run worse than the next-worst team, Detroit (5.20). The poor pitching has contributed to the Cubs’ 8-17 record this month, the third-worst in the majors.
Featured Game | Chicago Cubs vs. Cincinnati Reds
How to make Wednesday MLB parlays
The model also locked in two other best bets for Wednesday, including a play on an even bigger underdog. You can see the model’s MLB Wednesday best bets and parlay only at SportsLine.
What MLB picks should you target for a payout of 10-1? And what underdog does the model like on Wednesday? Visit SportsLine now to see the MLB best bets from an advanced model that is on a 59-51 roll on top-rated MLB money-line picks through 12 weeks.