When Jim Harbaugh took over as the Chargers head coach after leading Michigan to the national championship, many expected L.A. to play at a slower pace with a run-heavy offense. The sportsbooks certainly knew this as well, as long drives often lead to fewer points, so over-unders for the Chargers may have been lowered. All four Chargers games have gone Under the total total and only one was within a one-score margin of hitting the over. This week, the Chargers play the Broncos with an over/under of 35.5 points, according to the latest Week 6 NFL odds. It’s the lowest over/under in the Week 6 NFL schedule after opening at 42.5.
Should you play the Chargers (-3) or any side of the over/under when making your Week 6 NFL best bets and NFL betting picks? All of the Week 6 NFL lines are listed below, and SportsLine’s advanced computer model has all the NFL betting advice and NFL predictions you need to make the best Week 6 NFL picks now.
The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 6 of the 2024 NFL season on an incredible 10-2 hot streak on top-rated NFL picks this year. Longer term, it is on a 191-131 roll on top-rated NFL picks that dates back to the 2017 season and a 45-23 roll on top-rated NFL picks since Week 7 of 2022.
The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.
Now, it has turned its attention to the latest Week 6 NFL odds and NFL betting lines on the spread, money line, and over-under, and locked in picks for every NFL matchup. Head here to see every pick.
Top Week 6 NFL predictions
We can tell you one of the model’s strongest Week 6 NFL picks is that the Falcons (-6, 47) cover the spread versus the Panthers. Carolina’s offense looked anemic with Andy Dalton under center in last week’s loss to the Chicago Bears. Dalton completed 18 of 28 passes for 136 yards and one interception in the 36-10 setback. Running back Chuba Hubbard was the lone bright spot for the Panthers with 97 rushing yards and a touchdown.
However, Carolina’s defense was exposed in last week’s loss, giving up 304 passing yards to rookie quarterback Caleb Williams. On Sunday, the Panthers will face an Atlanta offense that has found its rhythm. Quarterback Kirk Cousins threw for a franchise record 504 yards in the Falcons’ 36-30 victory over the Buccaneers last Thursday. In addition, the Falcons are 12-5 in their past 17 meetings against the Panthers, while Carolina is just 1-13 in its last 14 matchups against an opponent from the NFC. That’s a big reason why Atlanta (-6) is projected to win by at least a touchdown and cover in well over 50% of simulations. See which other teams to pick here.
Another one of its Week 6 NFL betting predictions: the Commanders (+6.5, 51.5) cover on the road versus the Ravens in a game with the second-highest over-under of the week. If the regular season ended today, you could make a strong argument for Jayden Daniels to become the first rookie since Jim Brown in 1957 to win the NFL MVP. Washington leads the NFC East with a 4-1 record despite having the longest odds to win the division entering this season. Daniels leads the NFL in completion percentage (77.1%) and has the fifth-best quarterback rating.
This will be the matchup of arguably the two best dual-threat quarterbacks in the NFL right now with Daniels and Lamar Jackson. Although the Ravens have won three straight games, only one of those victories came by more than three points. There’s also an emotional element that can’t be ignored as the Ravens are coming off back-to-back crucial AFC victories over the Bills and Bengals and if there’s a letdown against an NFC opponent, Washington can upset the Ravens. The Commanders already have two victories over AFC North teams (Bengals and Browns), but all they need is to stay close to cover the spread on Sunday. Washington is also 4-1 ATS this year and the model projects the Commanders to cover the spread in over 50% of simulations. See which other teams to pick here.
How to make Week 6 NFL picks
The model has also made the call on who wins and covers in every other game on the Week 6 NFL schedule and just revealed two underdogs that outright win, potentially giving you a huge payday. You can only get every pick for every game at SportsLine.
So what NFL picks can you make with confidence, and which two must-see underdogs should you lock in now? Check out the latest NFL odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned well over $7,000, and find out.
Week 6 NFL betting odds, lines, spreads
Get Week 6 NFL picks at SportsLine
Sunday, Oct. 13
Jaguars vs. Bears — in London (-1, 44.5)
Commanders at Ravens (-6.5, 51.5)
Cardinals at Packers (-5.5, 47.5)
Texans at Patriots (+6.5, 37.5)
Buccaneers at Saints (+3.5, 41.5)
Chargers at Broncos (+3, 35.5)
Steelers at Raiders (+3, 36.5)
Falcons at Panthers (+6, 47)
Monday, Oct. 14
