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Monday Night Football odds, spread, line: Titans vs. Bills picks, predictions by expert on 20-7 roll

Monday Night Football odds, spread, line: Titans vs. Bills picks, predictions by expert on 20-7 roll

The red-hot Buffalo Bills can continue their strong start to the season when they take on the Tennessee Titans in a key Monday Night Football game at Nissan Stadium. The Bills (4-1) are on a four-game winning streak and lead the NFL in both scoring offense (34.4 points per game) and scoring defense (12.8). There have been two teams to finish No. 1 in both categories: the 1996 Packers, who won the Super Bowl, and the 1972 Dolphins, who finished undefeated. On Monday Night Football, the Bills take on a 3-2 Titans team that leads the AFC South and is coming off a victory over the Jaguars.

Kickoff is set for 8:15 p.m. ET. Buffalo is a six-point favorite in the latest Bills vs. Titans odds from Caesars Sportsbook, and the over-under for total points scored is 53.5. Before you make any Titans vs. Bills picks or Monday Night Football predictions, you need to see what SportsLine senior analyst Larry Hartstein has to say.

A former lead writer for Covers and The Linemakers, Hartstein combines a vast network of Vegas sources with an analytical approach he honed while working for Pro Football Focus. This season he has been on fire. Through five weeks Hartstein is 21-7-1 with his NFL picks, for a winning percentage of 75.0 and a profit of $1,305. With his last 26 picks, he is an absurd 21-5.

He also has had a keen eye for the tendencies of the Titans, posting an amazing 20-7-1 record (+1257) on his last 28 against the spread picks involving Tennessee. Anyone who has consistently followed him is way up.

Now, Hartstein has broken down Bills vs. Titans from all angles and just released his coveted best bets. You can head to SportsLine to see his NFL picks. Here are the NFL odds and betting lines for Titans vs. Bills: 

  • Bills vs. Titans spread: Buffalo -6
  • Bills vs. Titans over-under: 53.5 points
  • Bills vs. Titans money line: Buffalo -270, Tennessee +220
  • BUF: Bills lead the league in scoring defense (12.8 points per game)
  • TEN: RB Derrick Henry leads the league in rushing yards per game (128.0)

Featured Game | Tennessee Titans vs. Buffalo Bills

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Why the Bills can cover

Buffalo thrives on the road. The Bills have won five straight regular season road games, outscoring their opponents by a combined 121 points. They also have scored at least 34 points in each of those games. By contrast, Tennessee has lost three of its past five regular season home games.

In addition, Buffalo faces a Titans offense that has struggled protecting the quarterback this season. Tennessee has allowed 20 sacks, which is the most in the NFL. The Titans also have allowed a sack on 10.3 percent of their QB dropbacks, second most in the league behind only the Bears. The Bills have 14 sacks this season, tied for the fifth-most in the NFL.

Why the Titans can cover

Running back Derrick Henry has been his usual unstoppable self to start the season. Henry leads the league in rushing yards per game (128.0) and is tied for the league lead in total touchdowns (seven). He is on pace to shatter the NFL’s single-season records for rushing yards, rushing attempts and total touches.

In addition, Tennessee dominated Buffalo when these teams met last season. In Week 5 of last year, the Titans forced three turnovers, including two interceptions of Bills quarterback Josh Allen, and converted all of them into touchdowns in a 42-16 win. Tennessee quarterback Ryan Tannehill had an efficient game, completing 21-of-28 passes for 195 yards and three touchdowns.

How to make Bills vs. Titans picks

For Monday Night Football, Hartstein is leaning over on the point total, but he also says a critical X-factor makes one side of the Titans vs. Bills spread a must-back. He’s sharing what it is, and which side to back, only at SportsLine.

So who wins Bills vs. Titans on Monday Night Football? And what critical X-factor makes one side of the spread a must-back? Visit SportsLine now to see which side of the Bills vs. Titans spread you should be all over, all from the expert who’s a stellar 20-7 on his recent picks involving Tennessee, and find out.

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